OVERVIEW
Integrating agent-based modeling with computational fluid dynamics to predict biomass outcomes in bioreactors to form a generally applicable computational pipeline. We apply this pipeline to stirred tank bioreactors and recapitulate the biomass production as a function of impeller speed presented in the literature. We also apply this pipeline to model the behavior of cells that are seeded in an IBIDI flow chamber, a controlled system that will generate crucial experimental data for the development of models of cell behavior under shear stresses induced by fluids.
PROJECT PARTNERS
Industry Application and Benefits
Opensoure
Advancement to design better agitation & shear prosthesis for designing bioreactor
Current status
Used & tested by different cultivated meat startups
Fostered by research for higher impact
Funding Support
